Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Antihypertensive Drug

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43865   clinical trials with a EudraCT protocol, of which   7286   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    194 result(s) found for: Antihypertensive Drug. Displaying page 1 of 10.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2006-006981-40 Sponsor Protocol Number: hypertension2006-006981-40 Start Date*: 2007-05-03
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust jointly with University of Cambridge
    Full Title: Does the underlying haemodynamic abnormality determine response to antihypertensive therapy in patients with hypertension?
    Medical condition: Essential hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10004254 Benign essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) EE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-003410-12 Sponsor Protocol Number: RG_19-169 Start Date*: 2020-12-16
    Sponsor Name:University of Birmingham
    Full Title: Pregnancy ANtihypertensive Drugs: which Agent is best?
    Medical condition: Hypertension in pregnancy (chronic hypertension, gestational hypertension or pre-eclampsia)
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2021-001404-14 Sponsor Protocol Number: QGC001-3QG2 Start Date*: 2021-08-17
    Sponsor Name:Quantum Genomics
    Full Title: A Phase 3, Double-blind, Placebo-controlled and Open-label Efficacy and Long-term Safety Study of Firibastat (QGC001) Administered Orally, Once Daily, for Up to 48 Weeks in Patients with Difficult-...
    Medical condition: Treatment of patients with difficult-to-treat and/or treatment-resistant hypertension (HTN)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004866 10036695 Primary hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Prematurely Ended) HU (Ongoing) ES (Ongoing) CZ (Ongoing) IT (Ongoing) NL (Prematurely Ended) BE (Completed) BG (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-002545-32 Sponsor Protocol Number: CR0002 Start Date*: 2019-11-06
    Sponsor Name:Ablative Solutions, Inc
    Full Title: A Pivotal, Multicenter, Blinded, Sham Procedure-Controlled Trial of Renal Denervation by the Peregrine System™ Kit, in Subjects with Hypertension.
    Medical condition: Hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10047065 - Vascular disorders 10020772 Hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) FR (Ongoing) SE (Ongoing) BE (Ongoing) NL (Ongoing) IE (Ongoing) PL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-004509-29 Sponsor Protocol Number: QGC001-3QG1 Start Date*: 2020-04-27
    Sponsor Name:Quantum Genomics
    Full Title: A Phase 3, Double-blind, Placebo-controlled, Efficacy and Safety Study of Firibastat (QGC001) Administered Orally, Twice Daily, Over 12 Weeks in Difficult-to-treat/Resistant Hypertensive Subjects
    Medical condition: Treatment of hypertension (HTN) in difficult-to-treat and/or treatment resistant patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) DE (Completed) PL (Completed) ES (Ongoing) CZ (Completed) HU (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2008-003535-20 Sponsor Protocol Number: CS8635-A-E303 Start Date*: 2009-04-07
    Sponsor Name:DAIICHI SANKYO EUROPE GmbH
    Full Title: A RANDOMISED, DOUBLE-BLIND, ADD-ON STUDY OF HYDROCHLOROTHIAZIDE IN SUBJECTS WITH MODERATE TO SEVERE HYPERTENSION NOT ACHIEVING TARGET BLOOD PRESSURE ON OLMESARTAN MEDOXOMIL/AMLODIPINE FIXED DOSE CO...
    Medical condition: Essential hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020772 Hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) NL (Completed) FR (Completed) BE (Completed) ES (Completed) AT (Completed) CZ (Completed) DK (Completed) SK (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2014-002544-40 Sponsor Protocol Number: 5866 Start Date*: 2014-10-29
    Sponsor Name:Hôpitaux Universitaires de Strasbourg
    Full Title: THE TREATMENT OF HYPERTENSION ASSOCIATED WITH SEVERE PREECLAMPSIA. A RANDOMIZED CONTROLLED TRIAL OF URAPIDIL VERSUS NICARDIPINE. The URANIC trial.
    Medical condition: Hypertension associated with severe pre eclampsia
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-005344-95 Sponsor Protocol Number: 3004 Start Date*: 2012-06-15
    Sponsor Name:Steno Diabetes Center
    Full Title: Time course of the blood pressure lowering effect of liraglutide therapy in type 2 diabetes
    Medical condition: type 2 diabetes
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000631-25 Sponsor Protocol Number: 2007-000631-25 Start Date*: 2010-06-08
    Sponsor Name:KAROLINSKA INSTITUTET
    Full Title: THE ANTITTHROMBOTIC EFFECTS OF DOXAZOSIN AND RAMIPRIL IN ESSENTIAL HYPERTENSION
    Medical condition: ESSENTIAL HYPERTENSION
    Disease: Version SOC Term Classification Code Term Level
    12.1 10015488 Essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001898-25 Sponsor Protocol Number: DAR-311 Start Date*: 2006-09-21
    Sponsor Name:Gilead Sciences, Inc.
    Full Title: DORADO - Fixed Doses of Darusentan as Compared to Placebo in Resistant Hypertension A Phase 3 Randomized, Double-Blind, Placebo-Controlled, Multi-Center, Parallel Group Study to Evaluate the Effica...
    Medical condition: Resistant hypertension
    Disease: Version SOC Term Classification Code Term Level
    8.1 10038274 Refractory hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed) DE (Completed) GB (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-003547-23 Sponsor Protocol Number: DAR-312 Start Date*: 2007-11-15
    Sponsor Name:Gilead Sciences, Inc.
    Full Title: DORADO-AC - Optimized Doses of Darusentan as Compared to an Active Control in Resistant Hypertension A Phase 3 Randomized, Double-Blind, Placebo- and Active-Controlled, Multi-center, Parallel Grou...
    Medical condition: Resistant hypertension
    Disease: Version SOC Term Classification Code Term Level
    8.1 10038274 Refractory hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) GB (Completed) DE (Completed) BE (Completed) DK (Completed) ES (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2020-003647-28 Sponsor Protocol Number: NA Start Date*: 2020-12-09
    Sponsor Name:
    Full Title: Differences in antihypertensive drug levels in patients with hypertension: old vs young 2
    Medical condition: Hypertension Cardiovascular disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-000165-23 Sponsor Protocol Number: INFORM Start Date*: 2016-10-19
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and University of Cambridge
    Full Title: ComparIsoN oF Optimal Hypertension RegiMens (Part of the Ancestry Informative Markers in Hypertension (AIM HY) Programme – AIM HY-INFORM)
    Medical condition: Cardiovascular Hemodynamics
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004848 10005727 Blood pressure LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2018-004212-21 Sponsor Protocol Number: AMAG-423-201 Start Date*: 2019-05-24
    Sponsor Name:AMAG Pharmaceuticals, Inc.
    Full Title: A Phase 2b/3a, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study of the Efficacy and Safety of AMAG-423, a Digoxin Immune Fab, in Antepartum Subjects with Severe Pree...
    Medical condition: Severe Preeclampsia
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004868 10040444 Severe pre-eclampsia LLT
    Population Age: Adults Gender: Female
    Trial protocol: PL (Temporarily Halted) ES (Prematurely Ended) GB (Prematurely Ended) BE (Completed) RO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-021988-32 Sponsor Protocol Number: LUMI/10/ZOF- HYP/001 Start Date*: 2010-09-27
    Sponsor Name:LUSOFARMACO
    Full Title: A multicentre, multinational, randomised, double-blind, pilot, ascending dose for non responder, parallel group study on the therapeutic efficacy and safety of o.d. Zofenopril 30 mg plus HCTZ 12.5 ...
    Medical condition: elderly subjects (age > 65 years) affected by Isolated Systolic Hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050591 LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2016-002920-10 Sponsor Protocol Number: TRE-1486--0105-I Start Date*: 2016-09-14
    Sponsor Name:Klinikum der Universitaet Muenchen AoeR
    Full Title: TREAT-SVDs: EffecTs of Amlodipine and other Blood PREssure Lowering Agents on Microvascular FuncTion in Small Vessel Diseases
    Medical condition: Cerebral small vessel disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) NL (Ongoing) GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2008-003534-25 Sponsor Protocol Number: CS8635-A-E302 Start Date*: 2009-05-13
    Sponsor Name:DAIICHI SANKYO EUROPE GmbH
    Full Title: A randomised, double-blind, parallel group study evaluating the efficacy and safety of co administration of triple combinations of olmesartan medoxomil, amlodipine besylate, and hydrochlorothiazide...
    Medical condition: Essential hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020772 Hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LV (Completed) DE (Completed) NL (Completed) ES (Completed) BE (Completed) CZ (Completed) DK (Completed) BG (Completed) SK (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-001562-16 Sponsor Protocol Number: RGHT000278 Start Date*: 2006-11-01
    Sponsor Name:Royal Group of Hospitals Trust
    Full Title: Studies of insulin action in patients at increased vascular risk. Modulation by antihypertensive and endocrine replacement therapy.
    Medical condition: Protocol (a): Essential Hypertension Protocol (b): Hypertension in Type 2 Diabetes Protocol (c): Panhypopituitarism
    Disease: Version SOC Term Classification Code Term Level
    8.1 10022489 Insulin resistance LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-000605-12 Sponsor Protocol Number: notapplicable1 Start Date*: 2014-06-13
    Sponsor Name:
    Full Title: Thiazide diuretics versus calcium channel blockers for the treatment of calcineurin inhibitor-induced hypertension in patients with psoriasis or eczema: a single-center randomized cross-over trial.
    Medical condition: Hypertension, induced by the use of a Calcineurin Inhibitor (CNI)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-003568-20 Sponsor Protocol Number: RGR Start Date*: 2008-08-08
    Sponsor Name:Prof Alice Stanton
    Full Title: Renin Genotype and Response to Renin Angiotensin System Blockade.
    Medical condition: Hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: View results
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Sun Apr 28 02:33:46 CEST 2024 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA